Development of diagnostic kits for tuberculosis, non-tuberculous mycobacteria, and drug-resistant Development of In Vitro Diagnostic Medical Devices for tuberculosis, non-tuberculous mycobacteria, drug-resistance TB, etc
홈
R&D
Diagnostics
Diagnostics
Development of point of care test for simultaneous diagnosis of latent Tuberculosis(TB) and active TB
The most important aspect of TB control is to identify active TB patients as quickly as possible. TB progresses through stages of latent TB, incipient TB, subclinical TB, and active TB depending on the progression of complications after infection. Therefore, early diagnosis in the initial stages of tuberculosis onset is crucial.
KIT is developing a diagnostic kit that can diagnose TB and non-tuberculous antimicrobial pulmonary diseases early. To overcome the traditional method of latent TB infection testing, which involves blood collection, the kit collects peripheral blood from the finger. This enables the simultaneous diagnosis of subclinical TB, active TB, and non-tuberculous antimicrobial pulmonary diseases.
Methods for diagnosing active TB include culture, smear, and PCR. However, these methods have disadvantages such as long culture times, inaccuracies, and high costs. Through this project, it is anticipated that simultaneous diagnosis of latent TB infection and active TB will rapidly enable treatment and isolation of active TB patients and contacts.
Non-tuberculous mycobacteria are increasing globally, making the development of diagnostic methods for non-tuberculous mycobacteria through small biological samples extremely important.
Development of Non-Tuberculous Mycobacteria Identification Markers and Mixed Infection Analysis
While tuberculosis (TB) prevalence is decreasing worldwide, there is a rising trend in the prevalence of non-tuberculous mycobacteria (NTM) infections. Treatment for NTM varies depending on the species, underscoring the importance of accurate diagnosis.
The aim is to develop a rapid and accurate diagnostic technology for NTM through the discovery of NTM identification biomarkers. As part of the research, a Mycobacteria standard strain genome database is being established, and target genes for species identification and biomarker development are being selected to establish a species identification analysis method.
The validated species identification biomarkers will be applied to the development of on-site diagnostic kits.
